How It Works

Tirzepatide mimics two incretin hormones, GIP and GLP-1, which:

• Improve insulin secretion and glucose control
• Reduce appetite and food intake
• Slow gastric emptying, promoting fullness

This dual mechanism makes it more effective than standard GLP-1 agonists like semaglutide (Ozempic, Wegovy).

Clinical Benefits

Blood Sugar Control

• Lowers HbA1c by up to 2.24% in clinical trials
• Improves fasting glucose and insulin sensitivity

Weight Loss

• Clinical trials show up to 22.5% body weight loss
• In the SURMOUNT-1 trial, 36% of participants lost 25%+ of body weight

Cardiometabolic Benefits

• Lowers blood pressure and cholesterol
• Improves lipid profiles and fasting insulin levels

Prediabetes Reversal

• In 72 weeks, 95% of prediabetic participants returned to normal blood sugar levels

Comparison to Other Peptides

• More effective than semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity) in both weight loss and glucose control

Dosage & Administration

• Starting dose: 2.5 mg once weekly
• Maintenance dose: Increased gradually up to 15 mg
• Administration: Subcutaneous injection, once per week, with or without food

Always follow medical guidance when adjusting dosage.

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Ongoing Research

• Cardiovascular Studies: Investigating long-term heart health benefits
• New Applications: Potential treatments for NASH and obesity-related heart failure
• Combination Therapies: Exploring synergy with other metabolic treatments
• Long-Term Safety: Ongoing trials to evaluate extended use