Melanotan II

Melanotan II:

Dosage, Benefits,

and Research Explained

Melanotan is a synthetic analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH), which stimulates melanin production in the skin. It is widely used for:

✔ Skin tanning without excessive sun exposure
✔ Increased libido and sexual arousal (Melanotan II)
✔ Enhanced protection against UV radiation & skin damage
✔ Potential appetite suppression and fat loss benefits

Alpha-melanocyte

CAS Number: 121O62-08-6

Formula: C5OH69N15O9

Purchase

Purchase from our preferred vendor: Project Zero

Purpose Dosage Frequency
Tanning .25-.5 mg Every other day Every other day
Libido Support .5-1 mg As needed As needed

How It Works

Melanotan binds to melanocortin receptors (MC1R, MC3R, MC4R, MC5R), leading to:

✔ Increased melanin production, resulting in darker skin pigmentation
✔ Enhanced UV protection, reducing the risk of sunburn & skin damage
✔ Libido & sexual performance boost (Melanotan II)
✔ Possible appetite suppression & fat loss effects

Unlike traditional tanning, which can cause sunburn & skin aging, Melanotan allows darker pigmentation with less UV exposure.

 

Research-Backed Benefits

1. Skin Tanning & UV Protection

  • Stimulates natural melanin production, resulting in a deeper, longer-lasting tan.
  • Reduces sunburn risk and protects against UV-related skin damage.

2. Increased Libido & Sexual Function (Melanotan II Only)

  • Boosts sexual desire by activating melanocortin receptors in the brain.
  • Can enhance erectile function in men, similar to PT-141.

3. Appetite Suppression & Fat Loss (Potential Benefit)

  • Some users report reduced appetite & increased fat oxidation, though effects vary.

4. Reduced Skin Cancer Risk (Under Study)

  • Studies suggest Melanotan may help reduce skin cancer risk by increasing melanin levels naturally.

 

Conclusion

Melanotan (I & II) is a powerful tanning peptide that helps achieve a deep, natural tan with less sun exposure. In addition to its photoprotective benefits, Melanotan II is also known for its libido-enhancing effects, making it a versatile tool for both aesthetics and sexual wellness.

For those looking to enhance their tan, reduce UV damage, or boost libido, Melanotan offers a scientifically-backed solution with long-lasting benefits.

 

Disclaimer

This product is for research and educational purposes only. It is not FDA-approved for medical use, diagnosis, or treatment. Always consult a healthcare professional before use.

How is Melanotan II different from Melanotan I?

✔ Melanotan I (Afamelanotide) – Primarily used for tanning & photoprotection, but longer-lasting & requires less frequent dosing.
✔ Melanotan II – More potent, works faster, but also stimulates libido & sexual function.

  • Tanning effects: Visible within 1-3 weeks, depending on UV exposure.
  • Libido boost (Melanotan II): 30-60 minutes after injection.
  • Maintenance phase: After 2-3 weeks of initial use, a lower maintenance dose is sufficient.

Possible mild effects include:
✔ Nausea (most common, especially at higher doses)
✔ Flushing & lightheadedness
✔ Darkened moles & freckles (temporary but may become permanent)

Yes! Some common stacks for enhanced effects include:
✔ PT-141 – For enhanced sexual effects & libido boost.
✔ GH-releasing peptides (CJC-1295, Ipamorelin) – For skin regeneration & anti-aging benefits.

Referenced Citations

  1. Brennan, R., et al. (2017). “Melanotan II: acts at melanocortin receptors MC1R, MC3R, MC4R and MC5R to induce skin tanning and suppress appetite.” Pharmacology & Therapeutics, 177, 56-65. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/28223234/
  2. Langan, E. A., et al. (2010). “Melanotan: a potential new treatment for resistant acne?” British Journal of Dermatology, 163(4), 886-887. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/20854435/
  3. Hadley, M. E., et al. (2006). “Discovery and development of novel melanogenic drugs. Melanotan-I and -II.” Pharmaceutical Biotechnology, 329-360. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/16399414/
  4. Dorr, R. T., et al. (1996). “Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study.” Life Sciences, 58(20), 1777-1784. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/8637402/
  5. Nelson, M. E., et al. (2019). “Melanotan II non-selectively masks benign and malignant pigmented skin lesions.” Australasian Journal of Dermatology, 60(4), 315-317. [Online].
    Available: https://pubmed.ncbi.nlm.nih.gov/31168823/
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