N-Acetyl Semax

N-Acetyl Semax:

Dosage, Benefits,

and Research Explained

N-Acetyl Semax is a nootropic peptide known for its cognitive enhancement, neuroprotection, and mood-boosting effects. It is a synthetic derivative of the naturally occurring ACTH (Adrenocorticotropic Hormone) fragment but does not affect cortisol levels.

The N-Acetyl form of Semax is an enhanced version that offers greater potency and bioavailability, making it a powerful tool for mental performance and long-term brain health.

ACTH

CAS Number: 80714-61-0

Formula: C37H51NO10S

Purchase

Purchase from our preferred vendor: Project Zero

Purpose Dosage Frequency
Mood & Anxiety 300-600 mcg 1-2 x Daily
Cognative Function 300-800 mcg 1-2 x Daily

How It Works

N-Acetyl Semax stimulates the expression of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF), leading to:

✔ Enhanced neuroplasticity – Improves learning & memory
✔ Increased focus & cognitive speed – Supports work & study performance
✔ Mood stabilization & anti-anxiety effects – Helps reduce stress & depression
✔ Neuroprotection & brain repair – May protect against neurodegenerative diseases

Unlike traditional stimulants, Semax does not cause crashes or jitters, making it a safe and sustainable cognitive enhancer.

 

Research-Backed Benefits

1. Cognitive Enhancement & Memory Boosting

  • Increases BDNF & NGF, leading to faster learning, improved retention, and sharper recall.
  • Used by students, professionals, and biohackers to enhance productivity & creativity.

2. Mood & Anxiety Reduction

  • Acts as an anti-anxiety and antidepressant-like compound by regulating dopamine & serotonin.
  • Helps reduce brain fog, stress, and emotional instability.

3. Neuroprotection & Brain Health

  • Supports stroke recovery and neurodegeneration prevention.
  • May slow cognitive decline and improve brain resilience over time.

4. Physical & Mental Performance Enhancement

  • Boosts motivation, focus, and mental stamina.
  • Used by athletes and high-performers to sustain peak mental performance.

5. Anti-Fatigue & Stress Adaptation

  • Helps prevent mental burnout and cognitive fatigue.
  • Supports adrenal function and stress resistance.

 

Conclusion

N-Acetyl Semax is a powerful cognitive enhancer, mood stabilizer, and neuroprotective peptide that offers increased focus, memory, and mental performance without the crashes of traditional stimulants. Its ability to boost BDNF, regulate dopamine, and support brain health makes it one of the most effective nootropic peptides available.

Whether used for learning, productivity, stress management, or neuroprotection, Semax is a versatile and well-researched biohacking tool.

 

Disclaimer

This product is for research and educational purposes only. It is not FDA-approved for medical use, diagnosis, or treatment. Always consult a healthcare professional before use.

How is N-Acetyl Semax different from regular Semax?

✔ N-Acetyl Semax is stronger and more bioavailable, requiring lower doses for the same effects.
✔ Regular Semax is effective but requires slightly higher dosing.

  • Cognitive effects: Within 30-60 minutes.
  • Mood enhancement: Immediate relief within a few hours, with stronger effects after 1-2 weeks of use.
  • Neuroprotection & recovery: Benefits accumulate over weeks to months.

N-Acetyl Semax is well-tolerated, with minimal side effects. Possible mild effects include:
✔ Nasal irritation (if using a spray)
✔ Mild headache (rare, dose-dependent)
✔ Slight increase in motivation/restlessness at high doses

 

Yes! Some popular stacks for enhanced effects include:
✔ N-Acetyl Selank – For enhanced anxiety reduction & cognitive balance.
✔ Modafinil or Phenylpiracetam – For maximum focus & wakefulness.
✔ Lion’s Mane Mushroom – For synergistic neuroprotection & memory enhancement.

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